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ea0029p834 | Endocrine tumours and neoplasia | ICEECE2012

Expression of MAPK7 and CCNL1 in corticotrophinomas and functional analysis of miR-143 and miR-145 in corticotrophic tumoral lineage AtT20

Camargo R. , Paixao B. , Colli L. , Varanda W. , Rodrigues J. , Elias L. , Castro M.

Introduction: miR143 and 145 seem to be involved in the pathogenesis of cortitotrophinomas by modulating the expression of MAPK7 and CCNL1 genes, which protein products are involved in cell proliferation, differentiation, and cell cycle progression. Objective: To analyze the modulation of miR-143 and -145 in the expression of MAPK7 and CCNL1 genes in corticotrophinomas and corticotrophic tumoral lineage (AtT20).Material and Methods: The expression of MAP...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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